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TP2230 |
Fusion glycoprotein (92-106) [Human respiratory syncytial virus]
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Others
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Fusion glycoprotein (92-106) [Human respiratory syncytial virus] is a peptide with the sequence H2N-Glu-Leu-Gln-Leu-Leu-Met-Gln-Ser-Thr-Pro-Pro-Thr-Asn-Asn-Arg-OH, MW= 1741.96. |
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T38343 |
Quercetin pentaacetate
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Pentaacetylquercetin |
RSV
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Quercetin pentaacetate (Pentaacetylquercetin) has diverse biological activities, including antioxidant, anti-inflammatory, and anticancer properties. Quercetin pentaacetate interacts with RSV and inhibit the viral adhesi... |
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T12774 |
RSV-IN-1
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RSV
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RSV-IN-1 is an inhibitor of human respiratory syncytical virus (hRSV) and reduced the virus infectivity with IC50 value of 0.11 μM. |
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T4380 |
Ac-CoA Synthase Inhibitor1
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ACSS2 inhibitor |
RSV
,
Fatty Acid Synthase
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Ac-CoA Synthase Inhibitor1 (ACSS2 inhibitor) is the most potent and specific inhibitor of acetate-dependent acetyl-CoA synthetase 2 (ACSS2). |
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T9197 |
Sisunatovir hydrochloride
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RV521 HCl,Sisunatovir HCl |
RSV
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Sisunatovir hydrochloride (RV521 HCl) is an orally available inhibitor of the RSV-F protein that has exhibited potent efficacy against a panel of clinical isolates of RSV-A and RSV-B viruses in vitro (IC50 = 1.4 nM for R... |
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TQ0085 |
Presatovir
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GS-5806 |
RSV
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Presatovir (GS-5806) (GS-5806) is a novel, orally bioavailable RSV fusion inhibitor (mean EC50: 0.43 nM). |
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T7353 |
RSV604
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(S)-1-(2-Fluorophenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)urea |
RSV
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RSV604 ((S)-1-(2-Fluorophenyl)-3-(2-oxo-5-phenyl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)urea) is an inhibitor of respiratory syncytial virus (RSV) that binds to RSV nucleoprotein (Kd = 1.31 μM) |
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T2621 |
Rostafuroxin
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PST 2238 |
ATPase
,
RSV
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Rostafuroxin (PST 2238) has been used in trials studying the treatment of Essential Hypertension. |
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T0684 |
Ribavirin
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Tribavirin,ICN-1229,NSC-163039,RTCA |
Dehydrogenase
,
HCV Protease
,
DNA/RNA Synthesis
,
Antibiotic
,
AChR
,
RSV
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Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses. |
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T1024 |
Roflumilast
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B9302-107,BYK 20869,APTA 2217,BY 217 |
PDE
,
RSV
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Roflumilast (APTA 2217) is an orally available, long-acting inhibitor of phosphodiesterase (PDE) type 4 (PDE4), with anti-inflammatory and potential antineoplastic activities. Upon administration, roflumilast and its act... |
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T5539 |
GS-443902
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|
Nucleoside Antimetabolite/Analog
,
HCV Protease
,
SARS-CoV
,
DNA/RNA Synthesis
,
RSV
,
Drug Metabolite
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GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at least 12 weeks |
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T13401 |
Ziresovir
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AK0529,RO-0529 |
RSV
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Ziresovir (RO-0529) is a respiratory syncytial virus fusion protein (RSV F) inhibitor that inhibits RSV activity and can be used in the study of syncytial virus sensing. |
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T77132 |
Clesrovimab
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MK-1654 |
Others
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Clesrovimab (MK1654) is an anti-respiratory syncytial virus protein F human monoclonal antibody for the prevention and treatment of respiratory syncytial virus infections. |
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T26914 |
BTA-9881
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BTA9881,AZD9639,AZD-9639,BTA 9881,MEDI-564 |
RSV
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BTA-9881 is a novel RSV fusion inhibitor with oral activity and antiviral activity for the study of respiratory syncytial virus infections. |
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T60016 |
VV116
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GS-621763-d1,JT001 |
SARS-CoV
,
RSV
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VV116 (JT001) is a selective and orally active nucleoside antiviral agent against respiratory syncytial virus (RSV) and SARS-CoV-2 infection. |
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T29187 |
YM-53403
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|
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YM-53403 is an antiviral activity that effectively inhibits the replication of RSV strains belonging to subgroup A and subgroup B. It can be used to treat respiratory syncytial virus infections. |
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T26914L |
(R)-AZD 9639
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Others
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(R)-AZD 9639 is the R-isomer of AZD 9639, a novel respiratory syncytial virus (RSV) fusion inhibitor with antiviral activity. |
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T15621 |
Rilematovir
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JNJ-53718678,JNJ-678 |
EGFR
,
RSV
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Rilematovir (JNJ-678) is an inhibitor of fusion protein with antiviral activity and low cytotoxicity. Rilematovir can be used in studies about respiratory syncytial virus treatment. |
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T76907 |
Palivizumab
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Synagis,MEDI 493 |
RSV
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Palivizumab (MEDI 493) is a humanized RSV-specific monoclonal antibody that selectively inhibits epitopes at the F protein A antigenic site of RSV subtypes A and B for the prevention of respiratory syncytial virus infect... |
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T77100 |
Nirsevimab
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MEDI8897 |
RSV
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Nirsevimab (MEDI8897) is a recombinant human respiratory syncytial virus (RSV) monoclonal antibody with a modified Fc region. Nirsevimab efficiently targets RSV-B with a Kd value of 1.5 nM. Nirsevimab can be used to prev... |
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T17107 |
TMC353121
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Others
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TMC353121 is an effective inhibitor of respiratory syncytial virus fusion (pEC50: 9.9). |
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T12775 |
RSV604 (R enantiomer)
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RSV604 R enantiomer |
Others
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RSV604 R enantiomer is the R-enantiomer of RSV604. RSV604 is a respiratory syncytial virus (RSV) replication inhibitor. |
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T27271 |
Enzaplatovir
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BTA-585,BTA 585,BTAC585,BTA585,BTA-C585 |
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Enzaplatovir is an inhibitor of Respiratory Syncytial Virus (RSV), can be used as a viral fusion protein inhibitor. |
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T16439 |
PC786
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Others
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PC786 shows effective antiviral activity against RSV-A (IC50 <0.09 to 0.71 nM) and RSV-B (IC50, 1.3 to 50.6 nM). PC786 is an inhaled respiratory syncytial virus L protein polymerase inhibitor. |
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T26848 |
BMS-433771 free base
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BMS-433771,BMS 433771,BMS433771 |
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BMS-433771, a novel inhibitor of respiratory syncytial virus (RSV), binds the RSV F glycoprotein and inhibits membrane fusion. |
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T13046 |
Syncytial Virus Inhibitor-1
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Others
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Syncytial Virus Inhibitor-1 is a potent and orally bioavailable inhibitor of respiratory syncytial virus (RSV) fusion(EC50s of 0.002 μM, 0.004 μM, and 0.002 μM for RSV Long, RSV A2, and RSV B strains, respectively). |
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T70502 |
AZ-27
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|
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AZ-27 is a respiratory syncytial virus inhibitor which differentially inhibits different polymerase activities at the promoter. |
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T14195 |
ALS-8112
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Others
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T61856 |
Antiviral agent 10
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Antiviral agent 10 effectively inhibits the respiratory syncytial virus (RSV) [1], serving as a potent anti-viral compound. |
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T35177 |
Xibornol
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Bactacine,Nanbacine |
Antiviral
,
Antibiotic
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Xibornol (Nanbacine) has broad-spectrum antibacterial and antiviral activity and can be used to study Gram-positive bacterial infections and human respiratory syncytial virus and human coronavirus 229E infections. |
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T73268 |
HRSV-IN-1
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hRSV-IN-1 is an inhibitor of respiratory syncytial virus (hRSV) . |
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T68826 |
A33903
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A33903 is a 1,4-benzodiazepine analog that is being studied as a potential inhibitor of respiratory syncytial virus. This molecule was moderately active and demonstrated good pharmacokinetic properties. |
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T63253 |
AVG-233
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DNA/RNA Synthesis
,
RSV
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AVG-233 is an orally available RNA-dependent RNA polymerase (RdRp) inhibitor with antiviral activity that blocks respiratory syncytial virus and SARS-CoV-2 replication.AVG-233 is used in the study of respiratory syncytia... |
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T70451 |
Blancoxanthone
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Blancoxanthone is a molecule isolated from plants could also be potential drug candidates against COVID-19. Moreover, these could also show promising inhibitory effects against influenza-parainfluenza viruses, respirator... |
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T72753 |
RSV604 racemate
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A-60444 racemate |
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RSV604 (A-60444) racemate, a racemic mixture, exhibits lower potency against strains of respiratory syncytial virus (RSV) compared to its S-isomer. |
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T71856 |
FA-613
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FA-613 is a pyrimidine synthesis inhibitor which exhibits low micromolar antiviral activity against various influenza A and B virus strains, including the highly pathogenic influenza A strains H5N1 and H7N9, enterovirus ... |
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T36440 |
GS-441524 tris-isobutyryl ester
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GS-441524tris-isobutyryl ester is a prodrug form of the antiviral nucleoside analog and remdesivir metabolite GS-441524 .1It reduces the cytopathic effect of respiratory syncytial virus (RSV) in infected HEp-2 cells with... |
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T77005 |
Felvizumab
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|
|
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Felvizumab (SB 209763), a humanized IgG1κ monoclonal antibody, targets specific neutralizing epitopes on the F glycoprotein of Respiratory Syncytial Virus (RSV) [1] [2]. |
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T40114 |
RSV-IN-2
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|
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RSV-IN-2 is a powerful compound that acts as a dual inhibitor of both wild-type and mutant respiratory syncytial virus (RSV) fusion proteins. It efficiently inhibits the activity of these proteins, with an EC50 value of ... |
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T61704 |
RSV-IN-6
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|
|
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RSV-IN-6 (Compound 53) is a specific agent that effectively inhibits the respiratory syncytial virus (RSV) by targeting the M2-1 protein. It shows strong potency, with EC50 values of 4.4 μM and 1.3 μM against RSV-A and R... |
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T27668 |
JNJ-2408068
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R170591,R 170591,HE066500,R-170591,HE-066500,HE 066500 |
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JNJ-2408068 is an inhibitor of respiratory syncytial virus (RSV). JNJ-2408068 exhibited potent antiviral activity with EC50 of 2.1 nM. A similar inhibitory effect was observed in a RSV-mediated cell fusion assay (EC50= 0... |
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T72105 |
BMS-433771 dihydrochloride hydrate
|
|
|
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BMS-433771 dihydrochloride hydrate is a potent, orally active respiratory syncytial virus (RSV) inhibitor effective against both group A and B strains, demonstrating an average EC50 of 20 nM. It is utilized in researchin... |
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T61217 |
RSV-IN-3
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|
|
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RSV-IN-3 (Compound 1) serves as a dual inhibitor targeting both the respiratory syncytial virus (RSV) and influenza virus A (IAV), demonstrating anti-RSV efficacy with an EC50 of 32.70 μM [1]. |
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T60910 |
RSV-IN-4
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|
|
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RSV-IN-4 (Compound 2) has anti-RSV activity with EC50 of 11.76 μM. RSV-IN-4 is a respiratory syncytial virus (RSV) and influenza virus A (IAV) dual inhibitor [1]. |
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T76752 |
Motavizumab
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|
|
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Motavizumab (MEDI-524) is a monoclonal antibody targeting the respiratory syncytial virus (RSV). It is utilized in research focused on RSV infections in high-risk infants [1]. |
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T71291 |
EICAR
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|
|
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EICAR is a drug which acts as an inhibitor of the enzyme IMP dehydrogenase. It is a nucleoside derivative which has both anti-cancer and antiviral effects, and was originally developed for the treatment of leukemia, but... |
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T63433 |
RSV-IN-5
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|
|
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RSV-IN-5 is a potent dual inhibitor of wild-type and mutant respiratory syncytial virus (RSV) fusion proteins.RSV-IN-5 was able to act on wild-type A2 F protein and D486N mutant F protein with EC50 values of 2.0 nM and 8... |
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T69014 |
Sekikaic Acid
|
|
|
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Sekikaic acid is a phenolic lichen metabolite that has been found in H. obscurata and has diverse biological activities. It scavenges superoxide and DPPH radicals in cell-free assays when used at a concentration of 0.5 µ... |
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T62469 |
RSV/IAV-IN-3
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|
|
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RSV/IAV-IN-3 (compound 14'i) is a dual inhibitor of respiratory syncytial virus (RSV) (EC50: 2.92 μM) and influenza A virus (IAV) (EC50: 1.90 μM). RSV/IAV-IN-3 significantly inhibited luciferase activity in a dose-depend... |
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T38297 |
Ribavirin-13C5
|
Ribavirin-13C5 |
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Ribavirin-13C5is intended for use as an internal standard for the quantification of ribavirin by GC- or LC-MS. Ribavirin is an antiviral guanosine nucleoside analog.1,2Upon entry into cells, ribavirin is metabolized to a... |
